My state rather wen the other way.  When I arrived you could only get booze in a state-sanctioned liquor store.  But they've opened up so some (not all) grocery stores. Not as good as other states where anyone can sell booze, but better.

As far as I've been able to tell the GOP have breathlessly dug up "whistleblowers" who've reported that nothing at all untoward happened. That Hunter Biden benefitted from being the son of a Vice-President is undoubtable.  That he was hired into a position for which he was unqualified for nepotistic reasoning is similarly undoubtable.  However, none of these things are in any way illegal, no more than tRump "hiring" his children, similarly and spectacularly unqualified, to work in his White House.

GOP Congresscritters holding hearings have so far come up with zip.  Funny thing is even if they do, it isn't high crimes and misdemeanors committed during office, which is what impeachment is for.  None of this will stop them of course.

There is something wrong with the Universe, I find myself agreeing with Number 7. According to my readings DeSantis has raked in quite a bit of money from big GOP donors, what you all would call "Establishment Republicans".  tRump on the other hand has been drawing funds in from small donors, something DeSantis has been so far unable to do.  The rub is DeSantis will run out of big donors, they're small in number.  tRump will never run out of small ones.

I would say rather hard to say. The immune system is a very complex one and always evolving.

All of the lower responses mentioned don’t seem good on the face of it. But it is rather difficult to predict the actual clinical consequences of such physiologic changes. Which is of course why in-vitro studies are notoriously bad predictors of clinical outcomes.

I think this sort of article also belies the notion that all of biomedical research is hopelessly corrupted by big pharma. Which is not to say that our current regulatory regime does not distort things badly in some cases; however, the researchers here published what appears to be an honest and somewhat mixed result.

Peter, do you know anything about this journal?  I don't read the immunological literature, so I don't.

Pancreatic cancer is tough.  It's usually symptomatic until start metastasizing, and then its far too late.

Do you honestly think the Russians are going to stop in Ukraine?  They're trying to plug up holes through which invasion forces have historically come, and Ukraine is one of them.  The next ones involve both Romania and Poland.

The minute the Russians attack a NATO ally they get to fight us.  And based what happened in Ukraine I'm pretty certain they'll be annihilated by us in a matter of days.  At that point what's left retreats toward Russia which now has an existential crisis.  They think this is for their survival, so they either give up or use Nukes. If they use Nukes it gets really messy.

We don't want that war, we don't want the specter of a nuclear conflict.  So we supply the Ukrainians with whatever we can so long as we don't put boots on the ground, i.e. so long as we don't escalate.  This war will be fought sooner or later, the Russians want security from invasion.  I can't blame them, they've only been invaded a bunch of times.  So it gets fought in Ukraine, and it is in our vested interest to keep the Ukrainians well supplied with American arms.  Supplying Americans with weapons in Ukraine is way cheaper than us defending Poland, and if the Russians win in Ukraine that's what we'll be doing.