I think in general there's nothing to it.  But the place that I question has to do with employment. 

Would it be OK for someone to carte blanche not hire anyone from San Francisco because the city supports homosexuality?  I suspect when I put it that way then the reverse question of "Is it OK for a company to carte blanche not hire anyone from North Carolina because of HB2" becomes a more difficult one to deny.

Did Paypal commit a CRA violation by refusing to hire North Carolina people because of HB2?  Did Ringo commit a CRA violation by refusing to entertain fans, keeping in mind that hospitality facilities were the original target of the CRA?  I don't know.  But they are questions I'd like to have answered because there does seem to be a question about them.

Are you strong enough to challenge your own prejudices to arrive at an single principal that goes both ways?